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MOREHEAD, Ky. (AP) — Isaiah Smith ran for a career-high 205 yards on 31 carries and scored a touchdown and San Diego beat Morehead State 37-14 in a season-ending contest for both teams on Saturday. Grant Sergent threw for 184 yards and two touchdowns for San Diego (8-3, 6-2 Pioneer Football League) which ended the season with a four-game win streak and winners of six of seven. The Toreros finished in sole possession of second place in the PFL behind Drake (7-1), which clinched the league outright with a 49-10 win over Stetson on Saturday. Drake beat San Diego 30-28 on a walk-off field goal on Sept. 28 in Des Moines, Iowa. Bryce Patterson threw for 133 yards and a touchdown and James Louis ran for a touchdown for the Eagles (7-5, 5-3). ___ Get poll alerts and updates on the AP Top 25 throughout the season. Sign up here . AP collegebasketball: https://apnews.com/hub/ap-top-25-college-basketball-poll and https://apnews.com/hub/college-basketball

Ying Tang / NurPhoto via Getty Images GameStop ( GME ) swung to a profit in the third quarter, even as revenue fell year-over-year. Shares surged in extended trading Tuesday on the news. The video game retailer posted a profit of $17.4 million or 4 cents per share on revenue of $860.3 million, compared with a loss of $3.1 million or 1 cent per share on revenue of $1.08 billion a year ago. GameStop isn't widely covered by Wall Street, with Wedbush's Michael Pachter the lone analyst tracked by Visible Alpha. In a note Friday he reiterated an "underperform" rating and $10 price target for the stock, writing that "the company's planned return to growth faces insurmountable barriers." GameStop was in the meme stock spotlight again last week, when a cryptic post on X from social media influencer Keith Gill—better known as "Roaring Kitty" —sent the stock as much as 14% higher Thursday afternoon in a short-lived spike. GameStop shares, which popped over 10% in extended trading, were up about 54% for 2024 through Tuesday's close. Most of the gains this year came in May and June after Gill posted about the retailer on multiple occasions for the first time since a meme trading frenzy gripped the stock in late 2020 and early 2021. Read the original article on Investopedia

Clinical Validation Of Ourself Delivery Technology Published In Dermatologic Surgery: Tiered-Release VesiclesTM Poised To Revolutionize Skincare

If transplanting a human eye to restore vision in blind people is a possibility, it could very well come from one of Colorado’s largest medical campuses. A federal agency has tasked the University of Colorado Anschutz Medical Campus in Aurora to pursue vision restoration research. On Monday, the Advanced Research Projects Agency for Health (ARPA-H) announced it’s awarding $46.4 million in a five-year contract to help CU researchers find a cure for total blindness. ARPA-H, a federal agency, researches high-potential, high-impact biomedical and health research that requires extensive and more-comprehensive research. ARPA-H program manager Dr. Calvin Roberts, an experienced eye surgeon, said he first envisioned a partnership to provide research opportunities in what could be a revolutionary transplant procedure. “Our eyes are nothing more than the entry extension of your brain,” he said. “But what you would need to be able to do to transplant an eye would be what you need to be able to sever brain tissue, to reattach brain tissues, and we just don’t know how to do that. “But then if you actually could be successful, you could change the way health care is practiced.” The idea is to transplant a deceased person’s eyes to a living person, like a heart transplant — but much different, according to Roberts. Less than two years ago, Roberts said he met ARPA-H Director Renee Wegrzyn and the two agreed to pursue the challenging task. “Fully restoring sight is not yet a possibility, even though for more than 60 years we’ve been able to do human heart transplants,” Wegrzyn said, adding research team partners under ARPA-H will address barriers across the nation through other recipients of the program. Since ARPA-H started under the Biden administration two years ago, the agency has distributed more than $2 billion across more than 20 “high impact” medical programs nationwide, according to Wegrzyn. “If we are successful, not only what we’ll see is a transformation of an entire field, but also a de-risking of a technology so that there can be follow-on investment ... where so many biomedical innovations really, really do move very quickly,” Wegrzyn said. University of Colorado School of Medicine professors Kia Washington and Christene Huang will lead the project among CU researchers. “Currently, there has never been a successful whole human eye transplant for the restoration of vision,” Washington said. “We believe the great advancements over the last two decades in technology, transplantation surgery and regenerative medicine now make restoration of vision possible.” Washington added the hardest part of an eye transplant surgery is reconnecting the optic nerve and monitoring aftercare to make sure the brain is ready ”to receive the correct signals and is accepting the new eye.” Huang, the other project leader, said CU intends to “make it easier for the body to accept the new eye without rejecting it. Several other collegiate partners under ARPA-H assistance will collaborate with CU researchers in different ways. For instance, the University of Wisconsin and Indiana University will work to develop bioengineered “nerve bridges” to connect the new eye. Meanwhile, John Hopkins University and the University of Southern California will research other complications into eye transplants. “This is what science is all about,” University of Colorado President Todd Saliman said in a brief message at a news conference on Monday. U.S. Rep. Diana DeGette, D-Denver, who played a role in securing project dollars for CU’s medical campus, said she’s excited for the cutting-edge research. “When we see projects like this, this is what excites us. This $46.4 million award to study human eye transplantation is just a perfect example of what ARPA-H was designed to do, which is to fund cutting-edge research that has the potential to change lives in ways that industry alone and traditional government funded research alone cannot achieve.”How Xi Jinping is going back to Confucius to define China’s future

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Rachel Reeves and the five claims about her fiddling CVNEW YORK, Nov 21 (Reuters) - Just a few years after a bruising battle among Apollo's (APO.N) , opens new tab co-founders over succession, the alternative asset manager giant could face new upheaval if its chairman and chief executive both leave to work for U.S. President-elect Donald Trump. Wall Street was raking over the possibilities after Trump picked Jay Clayton , Apollo's board chair, to serve as Manhattan's top federal prosecutor, while sources said Marc Rowan , the firm's CEO, was being considered for the Treasury Secretary role. TD Cowen analysts said they were fielding calls on the implications and who might replace Rowan, as investors balanced the chances that senior government appointments could boost the industry with the challenge of changing the guard at the $722 billion manager. "Such an outcome would be a positive for the industry, as it likely tempers regulatory risk(s) while possibly accelerating the sector's entry into the retirement market, even beyond his official purview," the analysts said in a note to clients, referring to speculation about Rowan. Co-presidents Jim Zelter and Scott Kleinman, as well as a few other key executives could be likely successors as CEO, the TD Cowen analysts said. Apollo declined to comment. In a sign of Rowan's importance to Apollo, however, the alternative asset manager's stock slipped on Tuesday amid reports that he had emerged as a top contender for the Treasury job. It was up as much as 1.8% on Thursday afternoon. Rowan, who co-founded Apollo along with Leon Black and Josh Harris, stepped into the CEO role in 2021 after a messy succession process, set in motion by Black's association with convicted sex offender Jeffrey Epstein . An independent review commissioned by Apollo had found Black paid Epstein for some services but was not involved in any way with his criminal activities. The events also led to a dispute between the co-founders, which resulted in Harris departing the firm as well . Clayton, the former U.S. Securities and Exchange Commission chief, was appointed as its lead independent director to improve corporate governance in the wake of the events. Under Rowan, Apollo has been charting a new growth strategy, going far beyond its private equity origins. Apollo bought retirement services firm Athene Holding Ltd in an $11 billion all-stock transaction, a deal that came weeks after Rowan came out of a sabbatical to become the CEO. Bringing in-house an annuities provider has helped turn Apollo into one of the world's largest corporate credit investors. In its regulatory filings, Apollo said it depends on some key employees, although it does not name them. "The loss of the services of any of our key personnel or damage to their personal reputation could have a material adverse effect on our business," the firm says in its annual report. Sign up here. Reporting by Echo Wang and Isla Binnie in New YorkEditing by Alistair Bell Our Standards: The Thomson Reuters Trust Principles. , opens new tab Thomson Reuters Echo Wang is a correspondent at Reuters covering U.S. equity capital markets, and the intersection of Chinese business in the U.S, breaking news from U.S. crackdown on TikTok and Grindr, to restrictions Chinese companies face in listing in New York. She was the Reuters' Reporter of the Year in 2020. Thomson Reuters Isla Binnie is Reuters's New York-based Sustainable Finance Correspondent, reporting on how the worlds of business and finance are affected by and respond to environmental, social and governance issues. Isla previously covered a broad range of business, politics and general news in Spain and Italy, where she also moderated events. She trained with Reuters in London and covered emerging markets debt for the International Financing Review (IFR).

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