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In conclusion, the recent drop in oil prices to "innovative lows" in December has generated optimism among market participants, who are hopeful that prices could see further declines in the near future. However, the outlook for oil prices remains uncertain, with multiple factors at play that could influence the direction of prices in the coming months. As the global economy continues to navigate the challenges posed by the pandemic, the trajectory of oil prices will remain a key area to watch for investors, consumers, and policymakers alike.The rumor claims that a new set of regulations will be implemented that will require vehicles to undergo incredibly stringent inspections, with severe penalties for those who fail to meet the standards. However, there is no official announcement or credible source to support these claims. In fact, the authorities have not made any statements about any upcoming changes to vehicle inspection procedures.The A-share market in China has seen a remarkable start to the day as it edges closer to the 3500-point mark, influenced by significant positive developments across various sectors. The surge in stock prices has been primarily driven by a series of favorable macroeconomic and corporate news, bolstering investor confidence and fueling market optimism.

Food and agriculture will not be on the table in any trade deal talks with US, says Business Secretary

Gene Therapy to Target GD2 for Oncology is under clinical development by and currently in Phase I for Sarcomas. According to GlobalData, Phase I drugs for Sarcomas have a 77% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval. Gene Therapy to Target GD2 for Oncology overview Gene therapy is under development for the treatment of relapsed or refractory neuroblastoma, osteosarcoma and refractory or metastatic GD2-positive sarcoma. It is administered and constitutes modified natural Killer T cells expressing the third-generation chimeric antigen receptor (CAR) transduced with retroviral vector specific for the disialoganglioside GD2 and the suicide gene inducible caspase 9 (iCasp9). Bristol-Myers Squibb overview (BMS) is a specialty biopharmaceutical company. It is engaged in the discovery, development, licensing and manufacturing, marketing, distribution and sale of medicines and related medical products to patients with serious diseases. Its primary focus is on cancer, immunology, cardiovascular, and fibrotic diseases. The company offers its products across the world to wholesalers, retail pharmacies, medical professionals, hospitals and government entities. The company has an operational presence in the US, Switzerland, Puerto Rico, Ireland, and the Netherlands. The company conducts research to focus on the discovery and development of novel medicines that address diseases in areas of unmet medical need. BMS is headquartered in Princeton, New Jersey, the US. For a complete picture of Gene Therapy to Target GD2 for Oncology’s drug-specific PTSR and LoA scores, This content was updated on 12 April 2024 From Blending expert knowledge with cutting-edge technology, GlobalData’s unrivalled proprietary data will enable you to decode what’s happening in your market. You can make better informed decisions and gain a future-proof advantage over your competitors. , the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article. GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s .

Ultimately, the discussions in January will be pivotal in shaping the future of Ansu Fati at FC Barcelona. The club recognizes the importance of nurturing and retaining its top talents, and Fati's potential is seen as integral to the team's success in the years to come. By engaging in open and constructive dialogue with Fati's entourage, Barcelona hopes to reach a mutual understanding that will benefit both the player and the club.It was not the Wright Brothers but an Indian sage who invented flying, Uttar Pradesh governor Anandiben Patel said on Thursday, igniting a controversy involving facts and history as the former Bharatiya Janata Party (BJP) leader sought new education to students over these aspects. “Students should be told about how Wright Brothers are being wrongly credited for developing an airplane,” Patel declared during her first media interaction after completing five years in office. She asserted that ancient sage Maharishi Bharadwaj developed aviation technology first — a claim that contradicts records of Orville and Wilbur Wright achieved the first sustained, controlled, powered flight in Kitty Hawk, North Carolina, in 1903. The governor ventured further by describing Kumbhakarna, a character from the Hindu epic Ramayana, as “a technocrat who did not sleep for six months and instead worked in laboratories during the period.” This interpretation markedly differs from traditional religious texts, which portray Kumbhakarna as a mythological figure who slept for six-month intervals due to a divine boon or curse. These assertions follow her remarks at Lucknow University’s 66th convocation ceremony on December 6, 2023, where she elaborated on ancient Indian aviation. “Maharishi Bharadwaj’s Ashram, which still exists in Prayagraj, and his Yantra Sarvasva, called the encyclopaedia of machines, of which the Vymaanika Shastra is a part, revealed eight types of airplanes,” Patel, a former Gujarat CM, said. Scholars have noted that the Vymaanika Shastra, frequently cited in discussions of ancient aviation, was actually authored in the early 20th century and published in 1952 by G.R. Josyer. “Shivkar Bapuji Talpade, a resident of Mumbai, developed the first model of airplane eight years ahead of Wright Brothers... Talpade’s flew his airplane at a height of 1,800 feet,” Patel added. Talpade attempted to build an aircraft and fly it, too, is regarded as unverified with no reliable records. Patel, who took oath at Raj Bhavan on July 29, 2019, made these statements during her first comprehensive media interaction after completing five years in office.

By Katheryn Houghton and Arielle Zionts, KFF Health News (TNS) Tescha Hawley learned that hospital bills from her son’s birth had been sent to debt collectors only when she checked her credit score while attending a home-buying class. The new mom’s plans to buy a house stalled. Hawley said she didn’t owe those thousands of dollars in debts. The federal government did. Hawley, a citizen of the Gros Ventre Tribe, lives on the Fort Belknap Indian Reservation in Montana. The Indian Health Service is a federal agency that provides free health care to Native Americans, but its services are limited by a chronic shortage of funding and staff. Hawley’s local Indian Health Service hospital wasn’t equipped to deliver babies. But she said staff there agreed that the agency would pay for her care at a privately owned hospital more than an hour away. That arrangement came through the Purchased/Referred Care program, which pays for services Native Americans can’t get through an agency-funded clinic or hospital. Federal law stresses that patients approved for the program aren’t responsible for any of the costs. But tribal leaders, health officials, and a new federal report say patients are routinely billed anyway as a result of backlogs or mistakes from the Indian Health Service, financial middlemen, hospitals, and clinics. The financial consequences for patients can last years. Those sent to collections can face damaged credit scores, which can prevent them from securing loans or require them to pay higher interest rates. The December report , by the federal Consumer Financial Protection Bureau, found these long-standing problems contribute to people in Native American-majority communities being nearly twice as likely to have medical debt in collections compared with the national average. And their amount of medical debt is significantly higher. The report found the program is often late to pay bills. In some cases, hospitals or collection agencies hound tribal citizens for more money after bills are paid. Hawley’s son was born in 2003. She had to wait another year to buy a home, as she struggled to pay off the debt. It took seven years for it to drop from her credit report. “I don’t think a person ever recovers from debt,” Hawley said. Hawley, a cancer survivor, still must navigate the referral program. In 2024 alone, she received two notices from clinics about overdue bills. Frank White Clay, chairman of the Crow Tribe in Montana, testified about the impact of wrongful billing during a U.S. House committee hearing in April. He shared stories of veterans rejected for home loans, elders whose Social Security benefits were reduced, and students denied college loans and federal aid. “Some of the most vulnerable people are being harassed daily by debt collectors,” White Clay said. No one is immune from the risk. A high-ranking Indian Health Service official learned during her job’s background check that her credit report contained referred-care debt, the federal report found. Native Americans face disproportionately high rates of poverty and disease , which researchers link to limited access to health care and the ongoing impact of racist federal policies . White Clay is among many who say problems with the referred-care program are an example of the U.S. government violating treaties that promised to provide for the health and welfare of tribes in return for their land. The chairman’s testimony came during a hearing on the Purchased and Referred Care Improvement Act, which would require the Indian Health Service to create a reimbursement process for patients who were wrongfully billed. Committee members approved the bill in November and sent it for consideration by the full House. A second federal bill, the Protecting Native Americans’ Credit Act , would prevent debt like Hawley’s from affecting patients’ credit scores. The bipartisan bill hadn’t had a hearing by mid-December. The exact number of people wrongfully billed isn’t clear, but the Indian Health Service has acknowledged it has work to do. The agency is developing a dashboard to help workers track referrals and to speed up bill processing, spokesperson Brendan White said. It’s also trying to hire more referred-care staff, to address vacancy rates of more than 30%. Officials say problems with the program also stem from outside health providers that don’t follow the rules. Melanie Egorin, an assistant secretary at the U.S. Department of Health and Human Services, said at the hearing that the proposed legislation doesn’t include consequences for “bad actors” — health facilities that repeatedly bill patients when they shouldn’t. “The lack of enforcement is definitely a challenge,” she said. But tribal leaders warned that penalties could backfire. Related Articles Health | How America lost control of the bird flu, setting the stage for another pandemic Health | How to kick back, relax and embrace a less-than-perfect holiday Health | New childhood leukemia protocol is ‘tremendous win’ Health | For some FSA dollars, it’s use it or lose it at year’s end Health | Norovirus is rampant. Blame oysters, cruise ships and holiday travel White Clay told lawmakers that some clinics already refuse to see patients if the Indian Health Service hasn’t paid for their previous appointments. He’s worried the threat of penalties would lead to more refusals. If that happens, White Clay said, Crow tribal members who already travel hours to access specialty treatment would have to go even farther. The Consumer Financial Protection Bureau report found clinics are already refusing to see any referred-care patients due to the program’s payment problems. The bureau and the Indian Health Service also recently published a letter urging health care providers and debt collectors not to hold patients accountable for program-approved care. White, the Indian Health Service spokesperson, said the agency recently updated the referred-care forms sent to outside hospitals and clinics to include billing instructions and to stress that patients aren’t liable for any out-of-pocket costs. And he said the staff can help patients get reimbursed if they have already paid for services that were supposed to be covered. Joe Bryant, an Indian Health Service official who oversees efforts to improve the referral program, said patients can ask credit bureaus to remove debt from their reports if the agency should have covered their bills. Leaders with the Confederated Tribes of the Colville Reservation in Washington state helped shape the proposed legislation after their citizens were repeatedly harmed by wrongful billing. Tribal Chairman Jarred-Michael Erickson said problems began in 2017, when a regional Indian Health Service office took over the referred-care program from local staff. It “created a domino effect of negative outcomes,” Erickson wrote in a letter to Congress. He said some tribal members whose finances were damaged stopped using the Indian Health Service. Others avoided health care altogether. Responsibility for the Colville Reservation program transferred back to local staff in 2022. Staffers found the billing process hadn’t been completed for thousands of cases, worth an estimated $24 million in medical care, Erickson told lawmakers . Workers are making progress on the backlog and they have explained the rules to outside hospitals and clinics, Erickson said. But he said there are still cases of wrongful billing, such as a tribal member who was sent to collections after receiving a $17,000 bill for chemotherapy that the agency was supposed to pay for. Erickson said the tribe is in the process of taking over its health care facilities instead of having the Indian Health Service run them. He and others who work in Native American health said tribally managed units — which are still funded by the federal agency — tend to have fewer problems with their referred-care programs. For example, they have more oversight over staff and flexibility to create their own payment tracking systems. But some Native Americans oppose tribal management because they feel it releases the federal government from its obligations. Beyond wrongful billing, access to the referred-care program is limited because of underfunding from Congress. The $1 billion budget this year is $9 billion short of the need, according to a committee report by tribal health and government leaders. Donald Warne, a physician and member of the Oglala Sioux Tribe in South Dakota, called the proposed legislation a “band-aid.” He said the ultimate solution is for Congress to fully fund the Indian Health Service, which would reduce the need for the referred-care program. Back in Montana, Hawley said she braces for a fight each time she gets a bill that the referral program was supposed to cover. “I’ve learned not to trust the process,” Hawley said. ©2024 KFF Health News. Distributed by Tribune Content Agency, LLC.

6,000 inmates escape from a high-security prison as post-election violence roils Mozambique

Plenty of aspiring NFL playoff contenders with receiving needs will be making note of the name that just hit the free agent market: Odell Beckham, Jr. The three-time Pro Bowler and two-time All-Pro was released by the Miami Dolphins on Friday. However, that doesn't mean others should be lining up to sign him. The Washington Commanders (8-5) are one of those WR-needy teams, especially after losing Noah Brown to a potentially season-ending kidney injury this week. Brown had been Washington's starter opposite Terry McLaurin this season, and had caught 35 passes for 453 yards and a touchdown -- a memorable one , at that. Washington also already filled Brown's hole by signing K.J. Osborn, who was released by the New England Patriots days ago. Osborn struggled in New England, but had been productive for the Minnesota Vikings for the three prior seasons, so his signing can be justified by the logic that he simply was not a good fit with the Patriots. Beckham, on the other hand, is far more name than player at this stage of his career. There's a reason he has been on four NFL teams in the past four seasons , and it's because he is a shell of his All-Pro self. He has eclipsed 40 receiving yards per game one time since 2019, and this season he'd caught nine passes all year long with the Dolphins. Any team considering signing Beckham must realize that they are not signing the superstar who once dazzled the league with one-handed circus catches and was on pace to break all-time records. They are signing an injury-riddled 32-year-old who only remains on the NFL radar because of his past reputation. Washington would be wise to stick with Osborn as the short-term solution to its WR depth issue, and perhaps bring in another, cheaper option if necessary. Chasing after the headliner who would likely lack in production on the field is not the answer.Village People Founder Doubles Down on Letting Trump Use ‘Y.M.C.A.,’ Slams ‘Gay Anthem’ LabelAs I strolled through the bustling streets of Beijing, surrounded by the sights and sounds of a city steeped in history and culture, I couldn't help but reflect on my journey from Portugal to this vibrant metropolis. The decision to leave behind the familiarity of my homeland and embark on a new adventure in China had not been an easy one, but as I navigated my way through the maze of alleys and markets, I began to realize that I had found something truly remarkable – happiness.